Streptococcus pneumoniae serotypes isolated from the middle ear of Mexican children diagnosed with acute otitis media



Document title: Streptococcus pneumoniae serotypes isolated from the middle ear of Mexican children diagnosed with acute otitis media
Journal: Salud pública de México
Database: PERIÓDICA
System number: 000340496
ISSN: 0036-3634
Authors: 1
2
3
4
1
Institutions: 1Hospital Infantil de México "Federico Gómez", México, Distrito Federal. México
2Secretaría de Salud, Hospital Manuel Gea González, México, Distrito Federal. México
3Hospital Español, Unidad de Enfermedades Infecciosas, México, Distrito Federal. México
4Institutos Nacionales de Salud, México, Distrito Federal. México
Year:
Season: May-Jun
Volumen: 53
Number: 3
Pages: 207-211
Country: México
Language: Inglés
Document type: Artículo
Approach: Aplicado
Spanish abstract OBJETIVO: Conocer la etiología y serotipos de S. pneumoniae (Sp) en niños mexicanos, con otitis media aguda (OMA). MATERIAL Y MÉTODOS: Se incluyeron las muestras de pacientes con OMA del Hospital Infantil de México Federico Gómez (2002-2003), con cultivo positivo para Sp, (bacteriológicamente confirmados en el líquido del oído medio obtenido por timpanocentesis). Todos los Sp. fueron serotipificados. Se incluyeron 138 muestras de 135 niños con OMA. RESULTADOS: Sp. se aisló en 72 muestras de 70 niños: 60 (85.7%) eran previamente sanos y 10 (14.3%) eran inmunocomprometidos. Los serotipos más frecuentes fueron 6B y 19F (16.67%), y 6 A, 14 y 23F (15.27%). CONCLUSIONES: La distribución de los serotipos en niños con otitis media aguda fue similar a la reportada en ciudades en desarrollo y se observó que 63.9% de los serotipos aislados están incluidos en la vacuna conjugada 7-valente, 68.1% en la 10-valente y 83.3% en la 13-valente
English abstract OBJECTIVE: The aim of this study was to identify the etiology and the serotypes of S. pneumoniae (Sp) in Mexican children with acute otitis media (AOM). MATERIALS AND METHODS: The study includessamples frompatientsdiagnosed with AOM at the Federico Gomez Children's Hospital of Mexico (2002-2003),with positive culture for Sp bacteriologically confirmed in middle ear fluid obtained by tympanocentesis. All Sp were serotyped. A total of 138 samples from 135 children with AOM were included. RESULTS: Sp was isolated in 72 samples from 70 children. Sixty (85.7%) were previously healthy and 10 (14.3%) were immunocompromised. The most common serotypes were 6B and 19F (16.67%), and 6 A, 14 and 23F (15.27%). CONCLUSION: The distribution of serotypes among the children with AOM in the study is similar to that reported in developing cities, and 63.9% of the isolated serotypes are found to be included in the 7-Valent Pneumococcal Conjugate Vaccine (PCV), 68.1% in the 10-Valent PCV and 83.3% in 13-Valent PCV
Disciplines: Medicina
Keyword: Microbiología,
Salud pública,
Streptococcus pneumoniae,
Serotipos,
Otitis media
Keyword: Medicine,
Microbiology,
Public health,
Streptococcus pneumoniae,
Serotypes,
Otitis media
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