| Journal: | Revista médica del Hospital General de México |
| Database: | PERIÓDICA |
| System number: | 000268289 |
| ISSN: | 0185-1063 |
| Authors: | Soria Céspedes, Danny1 Lazos Ochoa, Minerva Ventura Molina, Vanesa |
| Institutions: | 1Universidad Nacional Autónoma de México, Facultad de Medicina, México, Distrito Federal. México |
| Year: | 2006 |
| Season: | Jul-Sep |
| Volumen: | 69 |
| Number: | 3 |
| Pages: | 138-143 |
| Country: | México |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Descriptivo |
| Spanish abstract | El coriocarcinoma gestacional (CG) es una de las neoplasia del trofoblasto gestacional que cuando es diagnosticada oportunamente es curable, incluso si presenta metástasis, pero es muy agresivo y mortal sin tratamiento. El objetivo del presente estudio es describir las características clínicas y anatomopatológicas diagnosticadas como coriocarcinoma gestacional en un periodo de 15 años en el Hospital General de México. Es un estudio retrospectivo, descriptivo y analítico de 22 autopsias. En 9,155 estudios de autopsia se diagnosticaron 22 (0.24%) como coriocarcinoma gestacional, con una frecuencia de 1.46 casos por año y edad promedio de 35.8 años. Todos los casos fueron precedidos de embarazo: molar (45.45%), aborto (22.73%) o embarazo eutócico (13.64%). Las manifestaciones clínicas fueron: sangrado transvaginal (54.5%), síntomas respiratorios (27.27%) y síntomas gastrointestinales (22.73%). Fueron diagnosticados clínicamente el 31.82%, con diagnóstico probable el 31.82% y no diagnosticados el 36.36%. Los sitios de metástasis fueron: pulmones (81.81%), hígado (59.09%) y cerebro (40.91%). El coriocarcinoma gestacional es una neoplasia mortal y subdiagnosticada, ya que con frecuencia no es sospechada clínicamente y el diagnóstico definitivo se efectúa en el estudio post mortem |
| English abstract | Gestational choriocarcinoma (GC) is one of the gestational trophoblastic diseases, if the diagnose is early it heals, even with metastasis, but it is very aggressive without treatment. The objective is to describe clinical and pathological features of autopsies with the diagnosis of gestational choriocarcinoma at Mexico´s General Hospital during the last fifteen years. It is a retrospective, descriptive and analytic study of 22 autopsies. Of 9155 autopsies reviewed, 22 were diagnosed as gestational choriocarcinoma (0.24%), with 1.46 cases per year and with an age average of 35.8 years. Every case was preceded by a pregnancy: molar (45.45%), abortions (22.73%) or eutotic pregnancy (13.64%). The clinical symptoms were vaginal bleeding (54.5%), respiratory symptoms (27.27%) and gastrointestinal symptoms (22.73%). The clinical diagnose was made in 31.82%, 31.82% with diagnose of probability and with no diagnosis in 36.36%. The most frequent sites of metastasis were: lungs (81.81%), liver (59.09%) and brain (40.91%). Gestational choriocarcinoma is subdiagnosed and it is mortal neoplasm when it is not suspected clinically and the definite diagnosis is made with the post mortem study |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Ginecología y obstetricia, Coriocarcinoma, Neoplasias, Anatomopatología |
| Keyword: | Medicine, Diagnosis, Gynecology and obstetrics, Choriocarcinoma, Neoplasias, Anatomopathology |
| Full text: | Texto completo (Ver HTML) |
