| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000425114 |
| ISSN: | 0034-9887 |
| Authors: | Rodríguez-Lagos, Andrea1 Sorlí, José V3 Calviño-Naveira, Michelle C2 Capell, Nuria Estañ1 |
| Institutions: | 1Hospital Universitario "Dr. Peset", Servicio de Análisis Clínicos, Valencia. España 2Grupo de trabajo (GdT) Sociedad Valenciana y Española de Medicina Familiar y Comunitaria, Genética Clínica y Enfermedades Raras, Valencia. España 3Universitat de Valencia, Valencia. España |
| Year: | 2018 |
| Season: | Nov |
| Volumen: | 146 |
| Number: | 11 |
| Pages: | 1351-1355 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone |
| Disciplines: | Medicina |
| Keyword: | Hematología, Inmunología, Terapéutica y rehabilitación, Amiloidosis, Rojo congo, Mieloma múltiple, Células plasmáticas |
| Keyword: | Hematology, Immunology, Therapeutics and rehabilitation, Amyloidosis, Congo red, Multiple myeloma, Plasma cells |
| Full text: | Texto completo (Ver PDF) |
