| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000454947 |
| ISSN: | 0034-9887 |
| Authors: | Figueroa Faúndez, Fernanda1 Vidal Rojas, Catalina1 Briones Muñoz, Vania1 Chandía Cabas, Mauricio1 |
| Institutions: | 1Universidad de Concepción, Facultad de Medicina, Concepción. Chile |
| Year: | 2022 |
| Volumen: | 150 |
| Number: | 3 |
| Pages: | 397-401 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure |
| Disciplines: | Medicina |
| Keyword: | Oncología, Hematología, Coagulación intravascular diseminada, Leucemia mieloide crónica, Citometría de flujo |
| Keyword: | Oncology, Hematology, Disseminated intravascular coagulation, Chronic myeloid leukemia, Flow cytometry |
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