| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000270832 |
| ISSN: | 0034-9887 |
| Authors: | Guzmán, María Antonieta1 Salinas, Jessica Toche, Paola Marinovic, María Angélica Gallardo, Ana María |
| Institutions: | 1Universidad de Chile, Hospital Clínico, Santiago de Chile. Chile |
| Year: | 2007 |
| Season: | Dic |
| Volumen: | 135 |
| Number: | 12 |
| Pages: | 1566-1571 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | Background: Immunotherapy can be used to treat allergic reactions to insect stings, specially bees and wasps. Aim: To report the experience with immunotherapy with aqueous extracts of hymenoptera venoms (bees and wasps). Material and methods: Ten patients aged 6 to 58 years were treated in an allergy center of a University Clinical Hospital. The medical indication for this treatment was, in all patients, anaphylactic reactions after hymenoptera stings. Immunotherapy was carried out using standardized vaccines (Aqueous extracts Venomvac LETI, Spain), applied in a traditional protocol, with subcutaneous injections. This protocol had two phases: a buildup phase (between weeks 1 and 13) and a monthly maintenance phase, from the 13th week. The monthly maintenance dose was 100 fig of hymenoptera specific venom extract. Results: Six patients had adverse reactions of different severity, during the treatment protocols and all had a good response to immediate therapeutic measures. After these events, they followed the protocol without problems. Two patients, treated with bee vaccines, suffered an accidental bee sting during the maintenance phase and they developed only local reactions. Conclusions: The lack of adverse reactions to bee stings in these two patients indicates the acquisition of clinical tolerance |
| Disciplines: | Biología, Medicina |
| Keyword: | Inmunología, Insectos, Toxicología, Veneno de abeja, Veneno de avispa, Inmunoterapia, Desensibilización |
| Keyword: | Biology, Medicine, Immunology, Insects, Toxicology, Bee venom, Wasp venom, Immunotherapy, Desensitization |
| Full text: | Texto completo (Ver HTML) |
