El gluten: Su historia y efectos en la enfermedad celíaca



Título del documento: El gluten: Su historia y efectos en la enfermedad celíaca
Revista: Revista médica de Chile
Base de datos: PERIÓDICA
Número de sistema: 000423878
ISSN: 0034-9887
Autores: 1
2
Instituciones: 1Universidad de Chile, Programa Doctorado en Nutrición y Alimentos, Santiago de Chile. Chile
2Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos, Santiago de Chile. Chile
Año:
Periodo: Oct
Volumen: 147
Número: 10
Paginación: 1319-1325
País: Chile
Idioma: Español
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés The global prevalence of celiac disease is of one person per 250 inhabitants. The disease is induced by gluten, a peptide contained in wheat, rye and barley that during small intestinal digestion generates smaller peptides. Some of these are resistant to hydrolysis and cross through the epithelium into the mucosa, inducing a cascade of immune reactions leading to the appearance of the disease in susceptible individuals. Gluten appeared as a consequence of agricultural practices initiated 10000 years ago in the Fertile Crescent of southwest Asia. Celiac disease epidemiology is complicated since consumption of gluten differs depending on the origin of populations. Treatment of celiac disease consists of withdrawing gluten from the diet, a task that becomes difficult in the long term. The concept of gluten-free food has changed along time. This article updates the concept of celiac disease, the history of gluten consumption in the world, the characteristics of a gluten free diet and the difficulties to adhere to it
Disciplinas: Química,
Medicina
Palabras clave: Bioquímica,
Química de alimentos,
Bioquímica,
Enfermedad celíaca,
Gliadina,
Gluten
Keyword: Biochemistry,
Food chemistry,
Biochemistry,
Celiac disease,
Gliadin,
Glutens
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