| Journal: | Revista do Instituto de Medicina Tropical de Sao Paulo |
| Database: | |
| System number: | 000547818 |
| ISSN: | 0036-4665 |
| Authors: | Medeiros, Carolina de Araújo1 Silva, Maria Beatriz de Araújo3 Oliveira, André Luiz Sá de4 Alves, Sílvia Marinho Martins2 Barros, Maria das Neves Dantas da Silveira2 Cavalcanti, Maria da Glória Aureliano de Melo2 Oliveira, Gênova Maria de Azevedo5 Carrazzone, Cristina de Fátima Velloso2 Oliveira Jr, Wilson Alves de2 Medeiros, Zulma Maria de1 |
| Institutions: | 1Universidade de Pernambuco, Programa de Pós-Graduação em Ciências da Saúde, Recife, Pernambuco. Brasil 2Universidade de Pernambuco, Pronto Socorro Cardiológico de Pernambuco, Recife, Pernambuco. Brasil 3Universidade de Pernambuco, Faculdade de Enfermagem Nossa Senhora das Graça, Recife, Pernambuco. Brasil 4Fundação Oswaldo Cruz, Instituto Aggeu Magalhães, Recife, Pernambuco. Brasil 5Secretaria Estadual de Saúde de Pernambuco, Programa de Chagas, Recife, Pernambuco. Brasil |
| Year: | 2022 |
| Volumen: | 64 |
| Country: | Brasil |
| Language: | Inglés |
| English abstract | Chagas disease is among the 21 neglected diseases according to the World Health Organization. This study aimed to investigate the morbidity and mortality distribution of Chagas disease for identifying areas with greater prevalences and deaths of the disease in Northeast Brazil. A population-based ecological study was performed from 2016 to 2018 using data on acute Chagas disease patients from the Disease Notification Information System, chronic cases from the Chagas Disease and the referral Heart Failure Outpatient Clinic in Pernambuco, and Chagas disease-related mortality from the Mortality Information System. The unit of analysis were Pernambuco State mesoregions. The indicators were spatialized into thematic maps on the occurrence and mortality of the disease per 100,000 inhabitants. No cases of acute disease were reported in the period analyzed. Data on 801 chronic Chagas disease patients were analyzed. The population showed an average age of 62 years, with female predominance. The most prevalent comorbidity was systemic arterial hypertension and cardiologic involvement without ventricular dysfunction. The average chronic disease occurrence rate was 3.2/ 100,000 people/ year. As for deaths in the mortality system; in total, 350 deaths were recorded, showing male predominance, age ≥ 60 years, and chronic disease with cardiac involvement as the main mortality cause. The annual average mortality proportion was 1.6/100,000 people. The chronic case distribution showed spatial heterogeneity, with the highest rates of chronic disease and deaths observed in two mesoregions, with the main cause of death being heart-related. This highlights the need for more specialized services in areas with higher burden of the disease to avoid delay in the patients’ care. |
| Keyword: | Chagas disease, Morbidity, Mortality, Brazil, Chronic disease |
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