COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient
Document title: COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient
Journal: Revista do Instituto de Medicina Tropical de Sao Paulo
Database:
System number: 000537117
ISSN: 0036-4665
Authors: 1
1
1
1
Institutions: 1Universidad Nacional de Colombia, Fundación Cardioinfantil, Bogotá, Arauca. Colombia
2Universidad del Rosario, Bogotá, Bogotá. Colombia
Year:
Volumen: 63
Country: Brasil
Language: Inglés
English abstract Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy.
Keyword: COVID-19,
Skin manifestations,
SARS CoV-2,
Shock
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