| Journal: | Revista do Instituto de Medicina Tropical de Sao Paulo |
| Database: | |
| System number: | 000537085 |
| ISSN: | 0036-4665 |
| Authors: | Barros, Eliana Nogueira Castro de1 Valle, Adriana P. do2 Braga, Patricia Emilia1 Viscondi, Juliana Y. K.1 Fonseca, Antonio R. B. da2 Vanni, Tazio1 Silva, Anderson da1 Cardoso, Maria Regina3 Villas Boas, Paulo José F.2 Precioso, Alexander Roberto1 |
| Institutions: | 1Instituto Butantan, Centro de Farmacovigilância Segurança Clínica e Gestão de Risco, São Paulo, São Paulo. Brasil 2Universidade Estadual Paulista, Faculdade de Medicina de Botucatu, Botucatu. Brasil 3Universidade de São Paulo, Faculdade de Saúde Pública, São Paulo, São Paulo. Brasil 4Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo. Brasil |
| Year: | 2021 |
| Volumen: | 63 |
| Country: | Brasil |
| Language: | Inglés |
| English abstract | This cross-sectional seroepidemiological survey presents the seroprevalence of SARS-CoV-2 in a population living in 15 Long-Term Care Facilities (LTCFs), after two intra-institutional outbreaks of COVID-19 in the city of Botucatu, Sao Paulo State, Brazil. Residents were invited to participate in the serological survey performed in June and July 2020. Sociodemographic and clinical characterization of the participants as well as the LTCF profile were recorded. Blood samples were collected, processed and serum samples were tested using the rapid One Step COVID-19 immunochromatography test to detect IgM and IgG anti-SARS-CoV-2. Among 209 residents, the median of age was 81 years old, 135 (64.6%) were female and 171 (81.8%) self-referred as being white. An overall seroprevalence of 11.5% (95% CI: 7.5% – 16.6%) was found. The highest seroprevalences of 100% and 76.9% were observed in LTCFs that had experienced COVID-19 outbreaks. Most residents with positive immunochromatography tests (70.8%) referred previous contact with a confirmed COVID-19 case. Although there was a relatively low seroprevalence of COVID-19 in the total number of elderly people, this population is highly vulnerable and LTCFs are environments at higher risk for COVID-19 dissemination. A well-established test for COVID-19 policies, the adequate characterization of the level of interaction between residents and the healthcare provider team and the level of complexity of care are crucial to monitor and control the transmission of SARS-CoV-2 in these institutions. |
| Keyword: | COVID-19, SARS-CoV-2, Seroprevalence, Long-term care facility, Elderly |
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