| Journal: | Revista do Colegio Brasileiro de Cirurgioes |
| Database: | PERIÓDICA |
| System number: | 000134496 |
| ISSN: | 0100-6991 |
| Authors: | Aun, Jacinto Jose Frem1 Oliveira, Mauricio Bonifacio Barbosa de Aun, Marcos Meireles Frem |
| Institutions: | 1Hospital Beneficencia Portuguesa, Campinas, Sao Paulo. Brasil 2Universidade Sao Francisco, Braganca Paulista, Sao Paulo. Brasil |
| Year: | 1998 |
| Season: | Mar-Abr |
| Volumen: | 25 |
| Number: | 2 |
| Pages: | 152-153 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Malacoplakia is a chronic granulomatous disease of unknown origin. However immunodeficiency states (immunossuppressive medication, old people, renal transplantation, leukaemia, diabetes mellitus, malnutrition and others) have been associated with patients with malacoplakia. An infectious cause of malakoplakia is suggested by the finding of coliform bacteria in the phagolysosomes of macrophages. The histologic study is characterized by a infiltrate of large macrophages (Hansenmann cells) with pathognomonic inclusions containing siderocalcific structures (Michaelis-Gutmann bodies). Most of the cases reported in literature, involve the genitourinary tract, but other structures can be affected (brain, bone, adrenal glands, lymph nodes, intestine, and others). A 66-year-old man whith a abdominal mass, went to our hospital with a colonic tumour diagnosis. The patient was submitted to a surgery, with resection of the rigth colon. The disease was invading a portion of the retroperitoneal tissue that was removed. The histopatologic study showed the pathognomonic sign of malakoplakia (Hansenmann cells and Michaelis-Gutmann bodies). Norfloxacin have been used to the complementar treatment with total cure of the patient |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Malacoplaquia, Colon |
| Keyword: | Medicine, Gastroenterology, Malacoplakia, Colon |
| Full text: | Texto completo (Ver PDF) |
