Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure



Document title: Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure
Journal: Revista de saude publica
Database:
System number: 000535779
ISSN: 0034-8910
Authors: 1
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2
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Institutions: 1Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo. Brasil
2Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro. Brasil
3Medical University of Graz, Division of Phoniatrics. iDN – interdisciplinary Developmental Neuroscience, Graz. Austria
4University Medical Center Göttingen & Leibniz ScienceCampus Primate Cognition, Child and Adolescent Psychiatry and Psychotherapy, Göttingen. Alemania
5Karolinska Institute, Center of Neurodevelopmental Disorders (KIND), Stockholm. Suecia
6University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA. Estados Unidos
Year:
Volumen: 55
Country: Brasil
Language: Inglés
English abstract We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015–2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.
Keyword: Child Development,
Language Development,
Cognition,
Motor Activity,
Zika Virus
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