Aldosterone and the mineralocorticoid receptor in insulin resistance and diabetes



Document title: Aldosterone and the mineralocorticoid receptor in insulin resistance and diabetes
Journal: Revista de la ALAD. Asociación Latinoamericana de Diabetes
Database: PERIÓDICA
System number: 000418773
ISSN: 2248-6518
Authors: 1
1
Institutions: 1Universidad de los Andes, Facultad de Medicina, Bogotá. Colombia
Year:
Volumen: 7
Number: 4
Pages: 203-211
Country: Colombia
Language: Inglés
Document type: Artículo
Approach: Analítico
English abstract Aldosterone is a key regulator of water and electrolyte metabolism, but recent evidence from multiple lines of research also identifies it as a major player in other chronic disorders, particularly diabetes and the metabolic syndrome. In this review, we summarize rel- evant aspects of aldosterone production, secretion, action, the way aldosterone and the mineralocorticoid receptor may impact energy metabolism, and useful take-home messages concerning mineralocorticoid antagonism in patients with type 2 diabetes mellitus
Disciplines: Medicina
Keyword: Metabolismo y nutrición,
Diabetes,
Síndrome metabólico,
Aldosterona,
Metabolismo,
Electrólitos
Keyword: Metabolism and nutrition,
Diabetes,
Metabolic syndrome,
Aldosterone,
Metabolism,
Electrolytes
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