What Did We Learn about Coronavirus Disease-19-Associated Acute Kidney Injury During the Pandemic?



Document title: What Did We Learn about Coronavirus Disease-19-Associated Acute Kidney Injury During the Pandemic?
Journal: Revista de investigación clínica
Database: PERIÓDICA
System number: 000452923
ISSN: 0034-8376
Authors: 1
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Institutions: 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Nefrología y Metabolismo Mineral, Ciudad de México. México
2Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Centro de Investigación de Enfermedades Infecciosas, Ciudad de México. México
3Universidad de Guadalajara, Centro de Ciencias de Salud, Guadalajara, Jalisco. México
4Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Monterrey, Nuevo León. México
Year:
Season: Nov-Dic
Volumen: 74
Number: 6
Pages: 287-301
Country: México
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Initial reports suggested that kidney involvement after coronavirus disease 19 (COVID-19) infection was uncommon, but this premise appears to be incorrect. Acute kidney injury can occur through various mechanisms and complicate the course of up to 25% of patients with COVID-19 hospitalized in our Institution, and of over 50% of those on invasive mechanical ventilation. Mechanisms of injury include direct kidney injury and predominantly tubular, although glomerular injury has been reported, and resulting from severe hypoxic respiratory failure, secondary infection, and exposure to nephrotoxic drugs. The mainstay of treatment remains the prevention of progressive kidney damage and, in some cases, the use of renal replacement therapy. Although the use of blood purification techniques has been proposed as a potential treatment, results to date have not been conclusive. In this manuscript, the mechanisms of kidney injury by COVID-19, risk factors, and the mainstays of treatment are reviewed
Disciplines: Medicina
Keyword: Nefrología,
Terapéutica y rehabilitación,
COVID-19,
Secuelas,
Lesión renal aguda,
Terapia de reemplazo renal,
Técnicas de purificación sanguínea,
Citocinas
Keyword: Nephrology,
Therapeutics and rehabilitation,
COVID-19,
Sequelae,
Acute kidney injury,
Renal replacement therapy,
Blood purification techniques,
Cytokines
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