Revista: | Revista de investigación clínica |
Base de datos: | PERIÓDICA |
Número de sistema: | 000452981 |
ISSN: | 0034-8376 |
Autores: | Catalán, Rodrigo1 Jiménez Ceja, José V2 Rincón Pedrero, Rodolfo1 Olivas Martínez, Antonio2 Martínez Rueda, Armando J1 Bazúa Valenti, Silvana1 Carrillo Pérez, Diego L2 Grajeda Medina, Leoneli I1 García Juárez, Ignacio3 Vilatobá, Mario4 Ortega Trejo, Juan A1 Pérez Villalva, Rosalba5 Bobadilla, Norma A1 Moreno, Erika1 Gamba, Gerardo1 |
Instituciones: | 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Nefrología y Metabolismo Mineral, Ciudad de México. México 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Medicine Interna, Ciudad de México. México 3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Gastroenterología, Ciudad de México. México 4Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Trasplantes, Ciudad de México. México 5Universidad Nacional Autónoma de México, Instituto de Investigaciones Biomédicas, Ciudad de México. México |
Año: | 2022 |
Periodo: | Mar-Abr |
Volumen: | 74 |
Número: | 2 |
Paginación: | 90-96 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Aplicado, descriptivo |
Resumen en inglés | Background: Early post-liver transplant (LT) acute kidney injury (AKI) has been associated with worse short-term and long-term outcomes, but the incidence and risk factors in our population are unknown. Methods: We designed a prospective, single-center, longitudinal cohort study to determine the incidence of AKI during the immediate postoperative period of LT, and to identify the risk factors associated with AKI after LT. Pre-operative and intraoperative variables were analyzed to determine if there was any correlation with the development of post-operative AKI. Results: Eighty-six patients were included in the final analysis; from them, 45 (52%) developed AKI in the following 30 days after LT. The presence of hepatic encephalopathy prior to LT was the factor most strongly associated with the development of AKI (Relative Risk 3.67, 95% Confidence Interval 1.08-8.95). Other factors associated with AKI development were male gender and a higher serum lactate during surgery. Conclusion: AKI was a frequent complication that significantly worsened the prognosis of LT recipients and was associated with an increased 30-day mortality rate. The presence of hepatic encephalopathy strongly predicted the development of severe AKI |
Disciplinas: | Medicina |
Palabras clave: | Nefrología, Insuficiencia renal, Trasplante de riñón, Lesión renal aguda, Encefalopatía, Diálisis |
Keyword: | Nephrology, Renal failure, Kidney transplantation, Acute kidney injury, Encephalopathy, Dialysis |
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