Cardioembolic Stroke: Risk Factors, Clinical Features, and Early Outcome in 956 Consecutive Patients
Document title: Cardioembolic Stroke: Risk Factors, Clinical Features, and Early Outcome in 956 Consecutive Patients
Journal: Revista de investigación clínica
Database: PERIÓDICA
System number: 000453181
ISSN: 0034-8376
Authors: 1
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Institutions: 1Hospital Universitari Sagrat Cor, Departamento de Neurología, Barcelona. España
2Universidad Ramón Llull, Facultad de Psicología, Educación Y Ciencia del Deporte, Barcelona. España
3Hospital Universitari Sagrat Cor, Biblioteca, Barcelona. España
4Institut Català de la Salut, Sistemas de Organización e Información, Barcelona. España
Year:
Season: Ene-Feb
Volumen: 73
Number: 1
Pages: 23-30
Country: México
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Background: There is little information about the early clinical features of cardioembolic stroke before complementary examinations. Objective: The aim of this study was to identify risk factors, clinical features, and early outcomes of cardioembolic stroke. Methods: Retrospective study based on prospectively collected data available from a university medical center hospital-based stroke registry. Consecutive patients diagnosed with cardioembolic infarction were selected and compared to those diagnosed with an atherothrombotic stroke. Predictors of cardioembolic infarction were assessed by multivariate analysis. Results: From a cohort of 4597 consecutive patients, we studied 956 patients diagnosed with cardioembolic infarction (80 years [standard deviation (SD) 9.14]; 63% women) and 945 with atherothrombotic infarction (77.01 years [SD 9.75]; 49.8% women). The univariate comparative analysis reported that advanced age (≥ 85 years), female gender, atrial fibrillation (AF), ischemic heart disease, and congestive heart failure were significantly more frequent in the cardioembolic group, whereas hypertension, diabetes, peripheral vascular disease, heavy smoking, hyperlipidemia, and previous transient ischemic attack were significant in the atherothrombotic group. In the logistic regression model, AF (odds ratio [OR] 15.75, 95% confidence interval [CI]: 12.14-20.42), ischemic heart disease (OR 3.12, 95% CI: 2.16-4.5), female gender (OR 1.56, 95% CI: 1.22-2.00), and sudden-onset (OR 1.97, 95% CI: 1.54-2.51), were independent significant predictors of cardioembolic stroke. Conclusions: Potential cardioembolic stroke requires a comprehensive evaluation, since early classification and identification through predictors would improve effective management
Disciplines: Medicina
Keyword: Sistema cardiovascular,
Accidentes cerebrovasculares,
Ancianos,
Fibrilación auricular,
Tromboembolismo intracraneal,
Factores de riesgo,
Etiología
Keyword: Cardiovascular system,
Stroke,
Aged,
Atrial fibrillation,
Intracranial thromboembolism,
Risk factors,
Etiology
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