| Journal: | Revista da Sociedade Brasileira de Medicina Tropical |
| Database: | PERIÓDICA |
| System number: | 000281932 |
| ISSN: | 0037-8682 |
| Authors: | Outani, Heloisa Novaes1 Monteiro, Alexandra Maria Vieira Boechat, Marcia Cristina Bastos Elsas, Pedro Paulo Xavier Azhar, Salman1 |
| Institutions: | 1Fundacao Oswaldo Cruz, Instituto Fernandes Figueira, Rio de Janeiro. Brasil |
| Year: | 1999 |
| Season: | Sep-Oct |
| Volumen: | 32 |
| Number: | 5 |
| Pages: | 557-570 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | This retrospective study reviews cases of ARDS (Adult Respiratory Distress Syndrome) treated and followed up from October 1988 to December 1990 in the Pediatric Intensive Care Unit of Instituto Fernandes Figueira/FIOCRUZ, Brazil. Clinical, radiological and histopathological features were analyzed and correlated with well defined stages of the disease process. Out of 459 cases, 49 (11%) were selected for further study. In 11 cases, histopathological examination (4 biopsies and 8 autopsies) was performed and then classified into one of the following phases: exsudative, cellular proliferative and late fibrotic. The work emphasizes the need for further clinical and experimental studies in order to define the mechanisms and the impact of this Syndrome in the pediatric population |
| Portuguese abstract | Estudo retrospectivo com revisão dos casos clínicos de Síndrome do Desconforto Respiratório Agudo, realizado no período de out/88 a dez/90 na Unidade de Pacientes Graves do Instituto Fernandes Figueira. Os autores estudaram as características clínicas, radiológicas e histopatológicas de acordo com o estágio evolutivo da doença. Dentre 459 casos estudados, foram selecionados 49 (11%). Onze casos tiveram exame anatomopatologico [biopsia (4), necropsia (8)] e foram classificados de acordo com o estágio evolutivo em: fase exsudativa inicial, fase proliferativa celular e fase proliferativa fibrótica. Houve correlação clínica radiológica e anatomopatológica nos casos confirmados com exame histológico. Os autores consideram importante estudos futuros em que a interação entre a pesquisa clínica e experimental permita o melhor conhecimento desta Síndrome na população pediátrica |
| Disciplines: | Medicina, Biología |
| Keyword: | Neumología, Anatomía e histología, Inmunología, Pulmones, Síndrome de distrés respiratorio agudo, Citocinas, Factor de necrosis tumoral |
| Keyword: | Medicine, Biology, Pneumology, Anatomy and histology, Immunology, Lungs, Acute respiratory distress syndrome, Cytokines, Tumor necrosis factor |
| Full text: | Texto completo (Ver HTML) |
