| Journal: | Revista brasileira de hematologia e hemoterapia |
| Database: | PERIÓDICA |
| System number: | 000306100 |
| ISSN: | 1516-8484 |
| Authors: | Domingos, Claudia R. Bonini1 Paixao, Beatriz M.C2 Zamaro, Paula J.A Chinelato, Ana Regina Leoneli, Guilherme G Silva-Junior, Wilson A |
| Institutions: | 1Universidade Estadual Paulista "Julio de Mesquita Filho", Departamento de Biologia, Sao Jose do Rio Preto, Sao Paulo. Brasil 2Fundacao Hemocentro, Ribeirao Preto, Sao Paulo. Brasil |
| Year: | 2005 |
| Season: | Abr-Jun |
| Volumen: | 27 |
| Number: | 2 |
| Pages: | 140-141 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Correspondencia |
| Approach: | Descriptivo |
| English abstract | Routine laboratorial diagnostic procedures for hemoglobin variants can be incorrect when based only on electrophoretic procedures. In this study we evaluated 264 blood samples with hemoglobin AS profile and of these, seven had a phenotype confirmed as hemoglobin A-Korle-Bu. Associated methodologies such as HPLC and molecular analyses supply necessary assistance for diagnosis and adequate genetic counseling |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Hematología, Laboratorio, Hemoglobinopatías, HPLC, Análisis molecular |
| Keyword: | Medicine, Diagnosis, Hematology, Laboratory, Hemoglobinopathies, HPLC, Molecular analysis |
| Full text: | Texto completo (Ver HTML) |
