| Journal: | RB. Radiologia brasileira |
| Database: | PERIÓDICA |
| System number: | 000302411 |
| ISSN: | 0100-3984 |
| Authors: | Lopes, Carlos de Oliveira1 Mas, Josepa Rigau I2 Zangaro, Renato Amaro3 |
| Institutions: | 1Instituto de Radioterapia do Vale do Paraíba, Brasil 2Universitat Rovira i Virgili, Facultat de Medicina i Ciencies de la Salut, Barcelona. España 3Universidade do Vale do Paraiba, Instituto de Pesquisa e Desenvolvimento, Sao Jose dos Campos, Sao Paulo. Brasil |
| Year: | 2006 |
| Season: | Mar-Abr |
| Volumen: | 39 |
| Number: | 2 |
| Pages: | 131-136 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | OBJECTIVE: To verify if the use of InGaAIP laser with 685 nm wave length can reduce the xerostomy incidence, the oral mucositis severity and the pain related to mucositis in patients with head and neck cancer submitted to radiotherapy. MATERIALS AND METHODS: Sixty patients presenting head and neck carcinoma were submitted to radiotherapy with daily doses of 1.8 to 2.0 Gy and a final dose of 45 to 72 Gy. The salivary volume was evaluated in the first and fifteenth days, at the end of the treatment and after 15 and 30 days. The oral mucositis was evaluated on a weekly basis. Twenty-nine patients were submitted to radiotherapy without laser and 31 were submitted to radiotherapy and laser with daily doses of 2 joules/cm² in predetermined areas of the oral mucosa and the parotid and submandibular glands. RESULTS: In the group submitted to radiotherapy and laser the incidence of mucositis (p < 0.001) and pain (p < 0.016) was significantly lower and the salivary volume (p < 0.001) was kept higher during and after the treatment. CONCLUSION: The group of patients submitted to radiotherapy and laser had lower incidence of xerostomy, oral mucositis and pain when compared to the group treated with radioteraphy without laser, producing statistically significant results |
| Portuguese abstract | OBJETIVO: Verificar se o uso do laser de InGaAlP com comprimento de onda de 685 nm pode reduzir a incidência de xerostomia, gravidade da mucosite oral e da dor associada à mucosite em pacientes portadores de câncer de cabeça e pescoço submetidos a radioterapia. MATERIAIS E MÉTODOS: Sessenta pacientes portadores de carcinoma de cabeça e pescoço foram submetidos a radioterapia com dose diária de 1,8 a 2,0 Gy e dose final de 45 a 72 Gy. O volume salivar foi medido nos dias um, 15, ao final do tratamento e após 15 e 30 dias, e a mucosite oral em avaliações semanais. Vinte e nove pacientes se submeteram a radioterapia sem laser e 31 foram submetidos a radioterapia e laser com dose diária de 2 joules/cm² em pontos pré-determinados da mucosa oral e glândulas parótida e submandibular. RESULTADOS: No grupo submetido a radioterapia e laser, a incidência de mucosite (p < 0,001) e dor (p < 0,016) foram significativamente menores e o volume salivar se manteve maior (p < 0,001) durante e após o tratamento. CONCLUSÃO: Os pacientes submetidos à associação de radioterapia e laser tiveram menor incidência de xerostomia, mucosite oral e dor quando comparados ao grupo de radioterapia sem laser, com resultados com significância estatística |
| Disciplines: | Medicina |
| Keyword: | Odontología, Oncología, Terapéutica y rehabilitación, Quimioterapia, Láser, Xerostomía, Mucositis, Radioterapia, Efectos adversos |
| Keyword: | Medicine, Dentistry, Oncology, Therapeutics and rehabilitation, Chemotherapy, Laser, Xerostomy, Mucositis, Radiotherapy, Adverse effects |
| Full text: | Texto completo (Ver HTML) |
