| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000313435 |
| ISSN: | 0100-4042 |
| Authors: | Guerra, Wendell1 Silva, Heveline Almeida, Mauro Vieira de Fontes, Ana Paula Soares |
| Institutions: | 1Universidade Federal de Juiz de Fora, Instituto de Ciencias Exatas, Juiz de Fora, Minas Gerais. Brasil |
| Year: | 2007 |
| Season: | Feb |
| Volumen: | 30 |
| Number: | 1 |
| Pages: | 56-58 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | In an attempt to reduce toxicity and widen the spectrum of activity of cisplatin and its analogues, much attention has been focused on designing new platinum complexes. This work reports the synthesis and characterization of novel compounds of the platinum (II) and platinum (IV) containing 2-furoic hydrazide acid and iodide as ligands. Although the prepared compounds do not present the classical structure of biologically active platinum analogues, they could be potentially active or useful as precursors to prepare antitumor platinum complexes. The reported compounds were characterized by ¹H NMR, 13C NMR, 195Pt NMR, IR and elemental analyses |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Antitumorales, Complejos de platino, Hidrazidas, Ligandos de iodo |
| Keyword: | Chemistry, Medicinal chemistry, Antitumoral agents, Platinum complexes, Hydrazides, Iodine ligands |
| Full text: | Texto completo (Ver HTML) |
