| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000198653 |
| ISSN: | 0100-4042 |
| Authors: | Gaudio, Anderson Coser1 Zandonade, Eliana |
| Institutions: | 1Universidade Federal do Espirito Santo, Centro de Ciencias Exatas, Vitoria, Espirito Santo. Brasil |
| Year: | 2001 |
| Season: | Sep-Oct |
| Volumen: | 24 |
| Number: | 5 |
| Pages: | 658-671 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Teórico, divulgación |
| English abstract | The present paper aims to bring under discussion some theoretical and practical aspects about the proposition, validation and analysis of QSAR models based on multiple linear regression. A comprehensive approach for the derivation of extrathermodynamic equations is reviewed. Some examples of QSAR models published in the literature are analyzed and criticized |
| Disciplines: | Química |
| Keyword: | Fisicoquímica y química teórica, Química farmacéutica, Química orgánica, Validación, Relación estructura-actividad, Modelos QSAR, Actividad biológica, Estructura química |
| Keyword: | Chemistry, Medicinal chemistry, Organic chemistry, Physical and theoretical chemistry, Validation, Structure-activity relationship, QSAR models, Biological activity, Chemical structure |
| Full text: | Texto completo (Ver HTML) |
