Planejamento racional de farmacos baseado em produtos naturais



Document title: Planejamento racional de farmacos baseado em produtos naturais
Journal: Quimica nova
Database: PERIÓDICA
System number: 000196060
ISSN: 0100-4042
Authors: 1
2
Institutions: 1Universidade Federal de Minas Gerais, Departamento de Quimica, Belo Horizonte, Minas Gerais. Brasil
2Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Quimica, Araraquara, Sao Paulo. Brasil
Year:
Season: Ene-Feb
Volumen: 24
Number: 1
Pages: 105-111
Country: Brasil
Language: Portugués
Document type: Artículo
Approach: Teórico, divulgación
English abstract In the area of drug discovery, natural products represent a myriad of templates for new lead discovery. It is, however, most unlikely that the bioactive principle itself shall become a drug; it is much more likely that a medicinal chemistry project needs to be initiated as soon the potency or selectivity or specificity of the new natural product candidate has been disclosed. Brazil has an enormous biodiversity where just a few has been disclosed. Nevertheless, it urges to initiate a joint collaboration in order to circumvent a major breakdown linking between natural products and medicinal chemistry in this country. This paper is intended to encourage people to follow up one of the most pushing forward enterprise that needs to be settled: the pharmaceutical industry
Disciplines: Química
Keyword: Fitoquímica,
Química farmacéutica,
Química orgánica,
Diseño de fármacos,
Fármacos,
Productos naturales,
Plantas medicinales,
Industria farmacéutica,
Brasil
Keyword: Chemistry,
Medicinal chemistry,
Organic chemistry,
Phytochemistry,
Drug design,
Drugs,
Natural products,
Medicinal plants,
Pharmaceutical industry,
Brazil
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