| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000313396 |
| ISSN: | 0100-4042 |
| Authors: | Bunhak, Elcio Jose1 Mendes, Elisabete Scolin2 Pereira, Nehemias Curvelo Cavalcanti, Osvaldo Albuquerque3 |
| Institutions: | 1Universidade Estadual do Oeste do Parana, Cascavel, Parana. Brasil 2Universidade Estadual de Maringa, Departamento de Engenharia Quimica, Maringa, Parana. Brasil 3Universidade Estadual de Maringa, Departamento de Farmacia e Farmacologia, Maringa, Parana. Brasil |
| Year: | 2007 |
| Season: | Abr |
| Volumen: | 30 |
| Number: | 2 |
| Pages: | 312-317 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Natural or modified chondroitin sulfate was incorporated in to polymethacrylate to obtain isolated films. The addition of polysaccharide to synthetic polymers occurred at different rates. Isolated films were micro and macroscopically characterized and swelling index and water vapor transmission were determined. Results indicated changed transparency and flexibility, coupled to their dependence on increase in polysaccharide concentration. A similar occurrence was reported in the permeability to water vapor and swelling degree. Films composed of modified chondroitin sulfate, 90:10 concentration, showed hydration levels, permeability and morphological properties which allow them to be applied as excipients in the development of new drug delivery systems |
| Disciplines: | Química |
| Keyword: | Química de polímeros, Sulfato de condroitina, Polimetacrilato, Indice de turgencia, Permeabilidad |
| Keyword: | Chemistry, Polymer chemistry, Chondroitin sulfate, Polymethacrylate, Swelling index, Permeability |
| Full text: | Texto completo (Ver HTML) |
