| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000313201 |
| ISSN: | 0100-4042 |
| Authors: | Vasconcellos, Mario Luiz A.A1 Miranda, Leandro S.M2 |
| Institutions: | 1Universidade Federal da Paraiba, Departamento de Quimica, Joao Pessoa, Paraiba. Brasil 2Universidade Federal do Rio de Janeiro, Nucleo de Pesquisas de Produtos Naturais, Rio de Janeiro. Brasil |
| Year: | 2006 |
| Season: | Jul |
| Volumen: | 29 |
| Number: | 4 |
| Pages: | 834-839 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | The Prins cyclization reaction has significantly advanced in the last years as demonstrated by a number of applications described in the literature. The objective of this report is to introduce this powerful synthetic methodology to the undergraduate and graduated student, since it is rarely presented in an organic synthesis formal course. This reaction is, in some cases, the methodology of choice for the preparation of natural products or drugs that present the tetrahydropyrane moiety in their structures. In this report we show some aspects of this reaction, including mechanism, scope and limitations |
| Disciplines: | Química |
| Keyword: | Química orgánica, Síntesis estereoselectiva, Ciclización de Prinz, Tetrahidropiranos |
| Keyword: | Chemistry, Organic chemistry, Stereoselective synthesis, Prins cyclization, Tetrahydropyrans |
| Full text: | Texto completo (Ver HTML) |
