Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’



Document title: Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000452449
ISSN: 0074-0276
Authors: 1
Institutions: 1Fundacao Oswaldo Cruz, Centro de Desenvolvimento Tecnologico em Saude, Rio de Janeiro. Brasil
Year:
Volumen: 117
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract In a previous publication, I stressed the fundamental importance of research for improving health using as an example the control of Chagas disease in the Americas.(1) For that purpose, I analysed the major scientific breakthroughs and public health events from the 1909 discovery of Chagas disease and its causative pathogen, Trypanosoma cruzi, by Carlos Chagas,(2) through the successful control of its transmission by insect vectors in large regions of the Southern Cone countries in the 90s.(3) In the twenty years since that publication, Brazil and Latin American countries had to cope with a number of serious public health threats, old and new: (i) recrudescence of well-known diseases, such as dengue and yellow fever; (ii) emergence of viral diseases that had been restricted to other continents (Zika, Chikungunya); (iii) new epidemics (H1N1) or (iv) pandemics (COVID-19). Are there still some lessons from that success story against a neglected disease of the 90s that would be relevant today in the context of these recent challenges?
Disciplines: Medicina
Keyword: Salud pública,
Enfermedades tropicales,
Enfermedades olvidadas,
Enfermedad de Chagas,
Trypanosoma cruzi,
Traslación
Keyword: Public health,
Tropical diseases,
Neglected diseases,
Chagas disease,
Translation,
Trypanosoma cruzi
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