| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000452439 |
| ISSN: | 0074-0276 |
| Authors: | Torres, Rosália Morais1 Correia, Dalmo2 Nunes, Maria do Carmo Pereira1 Dutra, Walderez O1 Talvani, André3 Sousa, Andréa Silvestre4 Mendes, Fernanda de Souza Nogueira Sardinha5 Scanavacca, Maurício Ibrahim6 Pisani, Cristiano6 Moreira, Maria da Consolação Vieira1 Souza, Dilma do Socorro Moraes de7 Oliveira-Junior, Wilson de8 Martins, Silvia Marinho8 Dias, João Carlos Pinto9 |
| Institutions: | 1Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais. Brasil 2Universidade Federal do Triangulo Mineiro, Uberaba, Minas Gerais. Brasil 3Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais. Brasil 4Universidade Federal do Rio de Janeiro, Rio de Janeiro. Brasil 5Fundacao Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro. Brasil 6Universidade de Sao Paulo, Instituto do Coracao, Sao Paulo. Brasil 7Universidade Federal do Para, Belem, Para. Brasil 8Universidade de Pernambuco, Recife, Pernambuco. Brasil 9Fundacao Oswaldo Cruz, Belo Horizonte, Minas Gerais. Brasil |
| Year: | 2022 |
| Volumen: | 117 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | In this chapter, the main prognostic markers of Chagas heart disease are addressed, with an emphasis on the most recent findings and questions, establishing the basis for a broad discussion of recommendations and new approaches to managing Chagas cardiopathy. The main biological and genetic markers and the contribution of the electrocardiogram, echocardiogram and cardiac magnetic resonance are presented. We also discuss the most recent therapeutic proposals for heart failure, thromboembolism and arrhythmias, as well as current experience in heart transplantation in patients suffering from severe Chagas cardiomyopathy. The clinical and epidemiological challenges introduced by acute Chagas disease due to oral contamination are discussed. In addition, we highlight the importance of ageing and comorbidities in influencing the outcome of chronic Chagas heart disease. Finally, we discuss the importance of public policies, the vital role of funding agencies, universities, the scientific community and health professionals, and the application of new technologies in finding solutions for better management of Chagas heart disease |
| Disciplines: | Medicina |
| Keyword: | Parasitología, Diagnóstico, Enfermedad de Chagas, Cardiomiopatia chagásica, Marcadores diagnósticos |
| Keyword: | Parasitology, Diagnosis, Chagas disease, Chagas cardiomyopathy, Diagnostic markers |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
