| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000420027 |
| ISSN: | 0074-0276 |
| Authors: | Marques, Bianca Cristina Leires1 Morgado, Mariza Gonçalves1 Guimarães, Monick Lindenmeyer1 |
| Institutions: | 1Instituto Oswaldo Cruz, Laboratorio de AIDS e Imunologia Molecular, Rio de Janeiro. Brasil |
| Year: | 2018 |
| Volumen: | 113 |
| Number: | 8 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | In Brazil, detection of the HIV-1 sub-subtype F1 has decreased with a simultaneous increase in detection of the recombinant FB and FC forms. In previous HIV-1 env molecular epidemiology studies in Rio de Janeiro, 11.4% of the detected sequences were of the F1 sub-subtype. With the goal of re-estimating the prevalence of the HIV-1 F1 sub-subtype, we performed extended analyses of these samples by examining five genomic regions, resulting in 3.3% being confirmed as F1. Moreover, genomic analysis of 11 of the 21 samples identified as F1 confirmed that nine were F1 and two were BF1. Considering the number of samples assayed, the prevalence of F1 was quite low, which supports the use of different genomic regions for the assessment of HIV-1 classification in countries where several subtypes and recombinant forms co-circulate |
| Disciplines: | Medicina |
| Keyword: | Virus, VIH, Epidemiología molecular, Genotipificación, Subtipos |
| Keyword: | Virus, HIV, Molecular epidemiology, Genotyping, Subtypes |
| Full text: | Texto completo (Ver HTML) |
