| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000452391 |
| ISSN: | 0074-0276 |
| Authors: | Haisi, Amanda1 Wu, Stacy2 Zini, Nathalia3 Silva, Maria Luana Cristiny Rodrigues da4 Malossi, Camila Dantas1 Cubas, Zalmir Silvino5 Cubas, Patrícia Hoerner6 Teixeira, Rodrigo Hidalgo Friciello7 Sousa, Mônica Shinneider de4 Lucena, Ricardo Barbosa8 Svoboda, Walfrido Kühl9 Osaki, Silvia Cristina2 Nogueira, Mauricio Lacerda3 Ullmann, Leila Sabrina1 Araújo-Junior, João Pessoa1 |
| Institutions: | 1Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Biotecnologia, Botucatu, Sao Paulo. Brasil 2Universidade Federal do Parana, Departamento de Ciencias Veterinarias, Palotina, Parana. Brasil 3Faculdade de Medicina de Sao Jose do Rio Preto, Laboratorio de Pesquisas em Virologia, Sao Jose do Rio Preto, Sao Paulo. Brasil 4Universidade Federal de Campina Grande, Patos, Paraíba. Brasil 5Refugio Biologico Bela Vista, Itaipu Binacional, Foz do Iguacu, Parana. Brasil 6Zoologico Bosque do Guarani, Foz do Iguacu, Parana. Brasil 7Zoologico Municipal Quinzinho de Barros, Sorocaba, Sao Paulo. Brasil 8Universidade Federal da Paraiba, Departamento de Ciencias Veterinarias, Areia, Paraiba. Brasil 9Universidade Federal da Integracao Latino-Americana, Foz do Iguacu, Parana. Brasil |
| Year: | 2022 |
| Volumen: | 117 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Zika virus (ZIKV) was discovered in 1947 with the virus isolation from Rhesus monkey (Macaca mulatta) in Uganda forest, Africa. Old World Primates are involved in a sylvatic cycle of maintenance of this arbovirus, however a limited knowledge about the role of New World primates in ZIKV transmission cycles has been established. OBJECTIVE This work aimed to investigate the presence of enzootic circulation of ZIKV in New World Primates from three Brazilian states: São Paulo, Paraíba, and Paraná. METHODS We analyzed 100 non-human primate samples collected in 2018 and 2020 from free-ranging and captive environments from São Paulo (six municipalities belonging to Sorocaba region), Paraíba (João Pessoa municipality), and Paraná (Foz do Iguaçu municipality) using reverse transcriptase quantitative polymerase reaction (RT-qPCR) assays, indirect enzyme-linked immunosorbent assay (ELISA), and plaque reduction neutralization test (PRNT). FINDINGS All samples (n = 141) tested negative for the presence of ZIKV genome from tissue and blood samples. In addition, all sera (n = 58) from Foz do Iguaçu’ non-human primates (NHPs) were negative in serological assays. MAIN CONCLUSION No evidence of ZIKV circulation (molecular and serological) was found in neotropical primates. In addition, the absence of antibodies against ZIKV suggests the absence of previous viral exposure of NHPs from Foz do Iguaçu-PR |
| Disciplines: | Medicina |
| Keyword: | Salud pública, Virus, Epidemiología, Virus del Zika, Ciclo de transmisión |
| Keyword: | Public health, Virus, Epidemiology, Zika virus, Transmission cycle |
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