Development and characterization of 5% mol Zn bioceramic in granular form



Document title: Development and characterization of 5% mol Zn bioceramic in granular form
Journal: Materials research
Database: PERIÓDICA
System number: 000312900
ISSN: 1516-1439
Authors: 1

2
3
4
Institutions: 1Universidade Federal do Rio de Janeiro, Instituto Alberto Luiz Coimbra de Pos-Graduacao e Pesquisa de Engenharia, Rio de Janeiro. Brasil
2University of Erlangen-Nuremberg, Department of Materials Science, Erlangen, Baviera. Alemania
3Universidade do Estado do Rio de Janeiro, Nova Friburgo, Rio de Janeiro. Brasil
4Universidade Federal Fluminense, Departamento de Biologia Celular e Molecular, Niteroi, Rio de Janeiro. Brasil
Year:
Season: Oct-Dic
Volumen: 9
Number: 4
Pages: 399-403
Country: Brasil
Language: Inglés
Document type: Nota breve o noticia
Approach: Experimental
English abstract Hydroxyapatite (HA) is capable of accepting substitute ions within its lattice, including zinc ions. Zinc is a trace element that activates the osteogenesis of osteoblastic cells and therefore plays an important role in the activity of alkaline phosphatase enzyme. The purpose of this work was to produce and characterize 5% mol Zn bioceramic in granular form (Zn-granules) for clinical applications and compare it with granules made from HA by using the same production route. Granules with addition of porogen agents were produced from powders of HA and zinc-containing HA by uniaxial pressing and heat treatment. The granules were subsequently ground and sieved. The results indicated that zinc contributed to the reduction of sample crystallinity and formed a biphasic structure after calcination at 1200 °C. Additionally, zinc release from granular material may have clinical applications as bone graft
Disciplines: Ingeniería,
Medicina,
Biología
Keyword: Ingeniería de materiales,
Traumatología y ortopedia,
Química farmacéutica,
Biomateriales,
Zinc,
Cerámica,
Tejido óseo,
Injertos,
Osteogénesis
Keyword: Engineering,
Medicine,
Biology,
Materials engineering,
Traumatology and orthopedics,
Medicinal chemistry,
Biomaterials,
Zinc,
Ceramics,
Bone tissue,
Grafts,
Osteogenesis
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