"In Situ" Generated "HCl": A Highly Efficient Catalyst for One-Pot Synthesis of 1H -Indazolo [1,2-b]phthalazine-1,6,11-triones and 1H- pyrazolo[1,2-b]phthalazine-5,10-diones under Solvent-Free Conditions
Document title: "In Situ" Generated "HCl": A Highly Efficient Catalyst for One-Pot Synthesis of 1H -Indazolo [1,2-b]phthalazine-1,6,11-triones and 1H- pyrazolo[1,2-b]phthalazine-5,10-diones under Solvent-Free Conditions
Journal: Journal of the Mexican Chemical Society
Database: PERIÓDICA
System number: 000377236
ISSN: 1665-9686
Authors: 1
1
Institutions: 1Hakim Sabzevari University, Department of Chemistry, Sabzevar. Irán
Year:
Season: Abr-Jun
Volumen: 58
Number: 2
Pages: 159-167
Country: México
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
Spanish abstract Se desarrolló una ruta sintética rápida para producir derivados de 1H-indazolo[1,2-b] ftalazina-1,6,11-trionas y 1H-pirazolo[1,2-b]ftalazina-5,10-dionas a través de reacciones de multicomponentes, en un solo paso, de varios aldehídos, 1,3-dicetonas cíclicas o acíclicas con: i) ftalhidrazida o ii) anhídrido ftálico-hidróxido de hidrazinio empleando 2,4,6-trichlorotriazina (TCT) húmeda como catalizador en ausencia de disolvente. Las características notables de este método son condiciones de reacción simples y suaves, el empleo de un catalizador barato y facilidad de aislamiento de los productos
English abstract The rapid and environmental synthetic route to produce 1H-indazolo[1,2-b] phthalazine-1,6,11-triones and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives have been developed via multi-component and one-pot reactions of various aldehydes, cyclic or acyclic 1,3-diketones with: i) phthalhydrazide or ii) phthalic anhydride-hydrazinium hydroxide using wet 2,4,6-trichlorotriazine (TCT) as catalyst under solvent-free conditions. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method
Disciplines: Química
Keyword: Química orgánica,
Síntesis química,
1H-indazolo[1,2-b] ftalazina-1,6,11-trionas,
1H-pirazolo[1,2-b]ftalazina-5,10-dionas,
Ftalhidrazida,
Aldehídos,
Reacciones libres de disolvente
Keyword: Chemistry,
Organic chemistry,
Chemical synthesis,
1H-Indazolo[1,2-b]phthalazine-1,6,11-triones,
1H-pyrazolo[1,2-b]phthalazine-5,10-diones,
Phthalhydrazide,
Aldehydes,
Solvent-free reactions
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