Synthesis of Analogues of 2-iodohexadecanal, a Regulator of Iodine Metabolism in the Thyroid Gland
Document title: Synthesis of Analogues of 2-iodohexadecanal, a Regulator of Iodine Metabolism in the Thyroid Gland
Journal: Journal of the Brazilian Chemical Society
Database: PERIÓDICA
System number: 000310852
ISSN: 0103-5053
Authors: 1
Institutions: 1Universite Libre de Bruxelles, Faculte des Sciences, Bruselas. Bélgica
Year:
Season: Ene
Volumen: 10
Number: 1
Pages: 1-12
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental
English abstract With the object of performing a structure-activity relationship study, we have synthesized several analogues of 2-iodohexadecanal [1], a regulator of iodine metabolism in the thyroid gland, differing by the chain length, the nature of the substituent, and/or the terminal functional group
Portuguese abstract Com o objetivo futuro de fazer um estudo da relação estrutura-atividade, foram sintetisados vários derivados do 2-iodo-hexadecanal [1], um regulador do metabolismo de iodo na glândula tireóide, que diferem no comprimento da cadeia, natureza do substituinte e grupo funcional terminal
Disciplines: Química
Keyword: Bioquímica,
Química farmacéutica,
Química orgánica,
Análogos químicos,
Metabolismo,
Tiroides
Keyword: Chemistry,
Biochemistry,
Medicinal chemistry,
Organic chemistry,
Chemical analogues,
Metabolism,
Thyroid gland
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