| Journal: | Journal of the Brazilian Chemical Society |
| Database: | PERIÓDICA |
| System number: | 000311212 |
| ISSN: | 0103-5053 |
| Authors: | Abdel-Kader, Maged S1 |
| Institutions: | 1University of Alexandria, College of Pharmacy, Alejandría. Egipto |
| Year: | 2003 |
| Season: | Ene |
| Volumen: | 14 |
| Number: | 1 |
| Pages: | 48-51 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental |
| English abstract | Seven compounds were isolated from the CHCl3 soluble fraction of the roots of Pituranthos tortuosus; in addition, mannitol was crystallized out of the total alcoholic extract. Using different spectroscopic techniques, the isolated compounds were identified as bergapten, graveolone, xanthotoxin, isopimpinellin, aesculetin dimethyl ether, stigmasterol glucoside, in addition to the new ester 4-methoxyphenylumbellate. The structure of the new ester was confirmed by total synthesis and it was found to be inactive in antimicrobial and cytotoxicity assays |
| Portuguese abstract | Sete compostos foram isolados, a partir das frações solúveis em CHCl3, de raízes de Pituranthos tortuosos; adicionalmente manitol foi cristalizado a partir do extrato alcoólico. Usando diferentes técnicas espectroscópicas os compostos isolados foram identificados como bergaptana, graveolana, xanthotoxinona, isopimpinela, dimetoxi aesculetina, 3-O-beta-glicopiranosil estigmasterol e também o novo éster umbelato de 4-metoxifenila. A estrutura do novo éster foi confirmada pela síntese completa e se mostrou inativo a testes antimicrobiais e de citotoxicidade |
| Disciplines: | Química, Biología |
| Keyword: | Fitoquímica, Angiospermas, Furanocumarinas, Glucósido de estigmasterol, 4-metoxifenilumbelato, Raíces, Pituranthos tortuosus, Apiaceae |
| Keyword: | Chemistry, Biology, Phytochemistry, Angiosperms, Furanocoumarins, Stigmasterol glucoside, 4-methoxyphenylumbellate, Roots, Pituranthos tortuosus, Apiaceae |
| Full text: | Texto completo (Ver HTML) |
