| Journal: | Jornal brasileiro de pneumologia |
| Database: | PERIÓDICA |
| System number: | 000297504 |
| ISSN: | 1806-3713 |
| Authors: | Antunes, Telma1 Barbas, Carmen Silvia Valente |
| Institutions: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
| Year: | 2005 |
| Season: | Jul |
| Volumen: | 31 |
| Pages: | 21-26 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | Wegener's granulomatosis is characterized by granulomatous necrotizing vasculitis that primarily affects the airways (upper and lower) and the kidneys. The diagnosis is made by analyzing the clinical and radiological manifestations (multiple pulmonary cavitations), together with the pathological findings and results of the test for cytoplasmic-pattern antineutrophil cytoplasmic antibodies. Treatment consists of corticosteroids and cyclophosphamide and leads to remission of the disease within one year in 90% of cases |
| Portuguese abstract | A granulomatose de Wegener caracteriza-se por vasculite necrosante granulomatosa que acomete preferencialmente vias aéreas superiores, inferiores e rins. Seu diagnóstico é feito associando-se as manifestações clínicas, radiológicas (multiplos nódulos escavados) e os achados anatomopatológicos e o anticorpo anticitoplasma de neutrófilos positivo. O tratamento com corticosteróides e ciclofosfamida leva a 90% de remissão da doença em 1 ano |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Neumología, Terapéutica y rehabilitación, Granulomatosis de Wegener, Vasculitis, Anticuerpos, Neutrófilo |
| Keyword: | Medicine, Diagnosis, Pneumology, Therapeutics and rehabilitation, Wegener granulomatosis, Vasculitis, Antibodies, Neutrophils |
| Full text: | Texto completo (Ver HTML) |
