| Journal: | Jornal brasileiro de patologia e medicina laboratorial |
| Database: | PERIÓDICA |
| System number: | 000297285 |
| ISSN: | 1676-2444 |
| Authors: | Melo, Murilo Rezende1 Melo, Keli Cardoso de2 Faria, Claudia Dutra Costantin |
| Institutions: | 1Santa Casa de Sao Paulo, Faculdade de Ciencias Medicas, Sao Paulo. Brasil 2Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
| Year: | 2006 |
| Season: | Ago |
| Volumen: | 42 |
| Number: | 4 |
| Pages: | 257-264 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | BACKGROUND: Hormone profile evaluation traditionally requires an expert review of results for adequate laboratory section test release. Analysis of these results using Boolean rules is an interesting alternative to reduce the number of results that require manual review. MATERIAL AND METHOD: We evaluated the utilization of Boolean rules using Instrument Manager software and Architect analyzer, mainly performing sex and thyroid hormones measurement. The intervention was evaluated on: a) number of rules and its easiness of construction; b) blind comparison of results evaluation by clinical pathologist (printed results) and set of rules in 940 consecutive tests. RESULTS: Rule creation was a complex and arduous task, especially due to hormonal profiles with several different request patterns. It was necessary to use a set of 153 Boolean (if then) rules, in a specific order. This set of rules agreed with expert opinion in 97.9% (920 tests). Rules hold 25 tests (2.7%) and the clinical pathologist only nine tests. There was discordance in 20 cases; rules did not hold only two cases: a beta-hCG in a male patient (that prompted the creation of a new rule) and a complete thyroid profile lacking only TSH request (pathologist opted to review the original request). CONCLUSION: Creation of an efficient set of Boolean rules proved to be a complex task requiring both technical and logics knowledge, but allowing optimization of laboratory workload. We achieved excellent concordance between the set of rules and clinical pathologist manual review, in a safe, fast and low cost system |
| Portuguese abstract | CONCLUSÃO: A criação de conjunto eficiente de regras booleanas é tarefa complexa que necessita de conhecimentos técnicos e de lógica, mas que permite a otimização do funcionamento do laboratório. Obtivemos excelente concordância entre o conjunto de regras criado e a liberação manual de patologista clínico, garantindo a segurança, a velocidade e o menor custo do sistema |
| Disciplines: | Medicina, Ciencias de la computación |
| Keyword: | Endocrinología, Inteligencia artificial, Matemáticas aplicadas, Hormonas sexuales, Hormonas tiroideas, Lógica, Computadoras, Programas, Algebra booleana, Validación, Software |
| Keyword: | Medicine, Computer science, Endocrinology, Artificial intelligence, Sexual hormones, Thyroid hormones, Logic, Computers, Programs, Boolean algebra, Validation, Software, Applied mathematics |
| Full text: | Texto completo (Ver HTML) |
