Comparacao de bulas de duas marcas de tiras reagentes utilizadas no exame quimico de urina



Document title: Comparacao de bulas de duas marcas de tiras reagentes utilizadas no exame quimico de urina
Journal: Jornal brasileiro de patologia e medicina laboratorial
Database: PERIÓDICA
System number: 000297303
ISSN: 1676-2444
Authors: 1
2
Institutions: 1Universidade Federal de Santa Catarina, Hospital Universitario, Florianopolis, Santa Catarina. Brasil
2Universidade Federal de Santa Catarina, Departamento de Ciencias Farmaceuticas, Florianopolis, Santa Catarina. Brasil
Year:
Season: Abr
Volumen: 42
Number: 2
Pages: 85-93
Country: Brasil
Language: Portugués
Document type: Artículo
Approach: Experimental, analítico
English abstract BACKGROUND: The urinalysis provides information about renal and urinary diseases, as well as about some extra renal diseases. The chemical examination of urine is done with reagent strips, which allows a quick, simple and economic analyze. OBJECTIVES: To compare drug labelings of two marks of reagent strips in urinalysis (Roche Combur10 Test® UX and Bayer Multistix® 10 SG). MATERIAL AND METHOD: The principles of pH, protein, glucose, ketone bodies, hemoglobin, bilirubin, urobilinogen, nitrite, specific gravity and leukocytes determinations, as well as the information about possible interferences were compared. RESULTS: There were differences in the detection’s reagents of some parameters, like urobilinogen (The Ehrlich’s reagent present in Multistix is less specific and more propense to analytical interferences than diazonium salt derived of methoxybenzene, used by Roche strip); the differences in the reagents used for nitrite, protein, glucose, bilirubin and hemoglobin determinations were relatively subtle. DISCUSSION: There was diversity of information about the potential interferences, which could be justified (at least partially) by differences in the reagents. Differences in the information about interferences had been detected between Spanish and Portuguese versions in the same product labeling, like the omission of some interferences in the product labeling in Portuguese. Great disparity in the reaction’s intensity and its expression in crosses were observed (e.g. for glucose), and it could lead to misunderstanding in the interpretation of laboratorial findings. CONCLUSION: These data reinforce the importance of standardizations in the urinalysis
Portuguese abstract Observou-se grande disparidade na avaliação da intensidade da reação e sua expressão em cruzes, como, por exemplo, no parâmetro glicose, o que pode levar a erros na interpretação do laudo laboratorial. CONCLUSÃO: As observações registradas reforçam a importância de padronizações no exame parcial de urina
Disciplines: Medicina
Keyword: Diagnóstico,
Análisis,
Orina,
Tiras reactivas,
Técnicas de laboratorio
Keyword: Medicine,
Diagnosis,
Analysis,
Urine,
Reagents,
Laboratory techniques
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