| Journal: | Ginecología y obstetricia de México |
| Database: | PERIÓDICA |
| System number: | 000453310 |
| ISSN: | 0300-9041 |
| Authors: | Abdelsalam, Walid A1 Etman, Waleed1 Harb, Ola A1 Abdelfattah, Ahmed Raafat1 Balata, Rawda1 Abohashim, Mohamed Fathy1 |
| Institutions: | 1Zagazig University, Zagazig, Sharqiya. Egipto |
| Year: | 2022 |
| Volumen: | 90 |
| Number: | 5 |
| Pages: | 427-433 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | OBJECTIVE: In the current study, we aimed to compare between radical surgery and fertility saving surgery in females with stage 1A-C EOC regarding recurrence rate and patients survival rates in addition to evaluating reproductive and obstetric outcomes for stage I EOC females who were managed by fertility saving surgery. PATIENTS AND METHODS: We prospectively identified 60 patients diagnosed with stage I EOC aged ≤ 40 years. Patients in the fertility-preservation group underwent salpingo-oophorectomy on the side of the affected ovary in addition to incisional biopsy or wedge excision of the ovary on the other side. Patients in the radical surgery group underwent total hysterectomy and bilateral salpingo-oophorectomy. We followed up all patients for 5 years to assess their reproductive and oncological outcomes. RESULTS: Patients in the fertility preservation surgery group were significantly younger (30 ± 4 versus 35 ± 5) (p < 0.001), their tumor sizes were smaller 3.4 ± 1.3 versus 6.0 ± 2.6 (p < 0.001), of lower grade (p = 0.011), earlier stage (p < 0.001) and has more mucinous histology than patients in the radical surgery group. There were no statistically significant differences between both groups regarding tumor recurrence or survival rates. Of 25 patients underwent fertility preservation surgery, 18/25 (72%) tried to get pregnant. 15/18 (83%) pregnancies were recorded, including 13 live births, 1 miscarriage, and 1 intrauterine fetal death. CONCLUSION: Fertility sparing surgery could be adequate alternative to radical surgery for young females with stage I EOC |
| Disciplines: | Medicina |
| Keyword: | Ginecología y obstetricia, Oncología, Cirugía, Cáncer epitelial de ovario, Fertilidad, Cirugía radical |
| Keyword: | Gynecology and obstetrics, Oncology, Surgery, Epithelial ovarian cancer, Fertility, Radical surgery |
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