| Journal: | Ecletica quimica |
| Database: | PERIÓDICA |
| System number: | 000366669 |
| ISSN: | 0100-4670 |
| Authors: | Parihar, M.S1 Khan, F1 |
| Institutions: | 1Dr. H.S. Gour University, Department of Chemistry, Sagar, Madhya Pradesh. India |
| Year: | 2008 |
| Season: | Ene-Mar |
| Volumen: | 33 |
| Number: | 1 |
| Pages: | 29-34 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental |
| Portuguese abstract | Stability constant (log b) and thermodynamic parameters of Cd2+ complexes with sulfonamide and cephapirin were determined by Polarographic technique at pH = 7.30 ± 0.01 and µ = 1.0 M KNO3 at 250°C. The sulfonamides were sulfadiazine, sulfisoxazole, sulfamethaxazole, sulfamethazine, sulfathiazole, sulfacetamide and sulfanilamide used as primary ligands and cephapirin as secondary ligand. Cd2+ formed 1:1:1, 1:2:1 and 1:1:2 complexes. The nature of electrode processes were reversible and diffusion controlled. The stability constants and thermodynamic parameters (DG, DH and DS) were determined. The formation of the metal complexes has been found to be spontaneous, exothermic in nature, and entropically unfavourable at higher temperature |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Sulfonamidas, Cefapirina, Complejos de cadmio, Polarografía, Constantes de estabilidad, Parámetros termodinámicos |
| Keyword: | Chemistry, Medicinal chemistry, Sulfonamides, Cephapirin, Cadmium complexes, Polarography, Stability constants, Thermodynamic parameters |
| Full text: | Texto completo (Ver HTML) |
