| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451800 |
| ISSN: | 1984-8250 |
| Authors: | Balbinot, Jessica Cristina1 Souza, Astrid Wiens2 Pontarolo, Roberto2 Boeira, Orli Dutra3 Silva, Edson Antonio Alves da4 Junges, Daniele Schaab Boff1 Reis, Camila Borges dos1 Venson, Rafael5 Oliota, Ana Flavia Redolfi1 |
| Institutions: | 1Universidade Estadual do Oeste do Parana, Cascavel, Parana. Brasil 2Universidade Federal do Parana, Departamento de Farmacia, Curitiba, Parana. Brasil 310ª Regional de Saude do Parana, Cascavel, Parana. Brasil 4Universidade Estadual do Oeste do Parana, Centro de Ciencias Tecnologicas e Exatas, Cascavel, Parana. Brasil 5University of Glasgow, School of Medicine, Dentistry and Nursing, Glasgow, Lanark. Reino Unido |
| Year: | 2022 |
| Volumen: | 58 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | The objective of this study is to validate the specific questionnaire for Hepatitis B HBQOL (Hepatitis B Quality of Life Instrument, version 1.0) for the Brazilian version, in addition to testing its applicability in patients with hepatitis B under treatment and comparing the quality of life between patients using first-line drugs (tenofovir and entecavir). For the validation, the back-translation technique was used in a sample of 47 patients. Factor analysis was performed between the items in each domain of the questionnaire and the internal consistency was calculated using Cronbach's α coefficient. In assessing the applicability of the validated questionnaire, interviews were carried out with 124 patients. Sociodemographic and treatment data were collected to characterize the sample and perform correlation analyzes. The results demonstrate that the Brazilian version of the questionnaire was successfully validated. In the analysis carried out among the 124 patients, the domains psychological well-being and stigma obtained the highest scores in quality of life and the lowest level of education conferred better results in these two domains. The comparison between tenofovir and entecavir showed no significant difference in patients' quality of life. The use of this validated instrument can make therapeutic decisions more rational |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Terapéutica y rehabilitación, Hepatitis crónica, Hepatitis B, Calidad de vida |
| Keyword: | Gastroenterology, Therapeutics and rehabilitation, Chronic hepatitis, Hepatitis B, Quality of life |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
