| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451977 |
| ISSN: | 1984-8250 |
| Authors: | Greta, Ulikhanyan1 Hasmik, Galstyan1 Karine, Dumanyan1 Margarita, Beglaryan2 Gayane, Poghosyan3 Vladimir, Shekoyan3 Hrachya, Ananikyan4 Violeta, Ananikyan4 Vigen, Goginyan5 Ghukas, Ulikhanyan6 Sona, Taschyan7 Naira, Chichoyan1 |
| Institutions: | 1Yerevan State Medical University after M. Heratsi, Department of Pharmacognosy, Yerevan. Armenia 2Yerevan State Medical University after M. Heratsi, Department of Pharmaceutical Management, Yerevan. Armenia 3Yerevan State Medical University after M. Heratsi, Department of Medical Microbiology, Yerevan. Armenia 4National Academy of Sciences, Scientific-Technological Center of Organic and Pharmaceutical Chemistry, Yerevan. Armenia 5National Academy of Sciences, Scientific and Production Center of Armbiotechnology, Yerevan. Armenia 6Armenian Pharmaceutical Association, Yerevan. Armenia 7Yerevan State Medical University, Department of Medical Biology, Yerevan. Armenia |
| Year: | 2022 |
| Volumen: | 58 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | The aim of the current study was to determine the chemical constituents of essential oil and to study the antibacterial and antioxidant activities of essential oil and the extracts obtained from the raw material of Ziziphora wild growing in the floras of Armenia and Artsakh cultivated in the hydroponic conditions. The essential oils were obtained by the method of hydro-distillation. The determination of the essential oil constituents were performed by the GC-MS method. Agar disk diffusion method was used to study the antimicrobial activity of essential oils. The antioxidant activity determination was carried out DPPH test by the spectrophotometric method, at the same time IC50 was determined. The highest values of the essential oils yield (1.25 ± 0.01%) and IC50 13.83±0.218(x10-5)g/l) were received for the plant cultivated in hydroponic conditions. For the first time in the above studied samples, by the method of GC-MS more than 70 components were revealed. The results of the study showed that essential oils of Ziziphora exhibit antimicrobial activity and the extracts revealed relatively expressed antioxidant activity. The study results show the future prospects of the use of Ziziphora not only as the source of flavonoids and essential oils, but also antimicrobial and antioxidant agents |
| Disciplines: | Biología, Química |
| Keyword: | Angiospermas, Fitoquímica, Aceites esenciales, Actividad antimicrobiana, Actividad antioxidante, Ziziphora clinopodioides, Lamiaceae |
| Keyword: | Angiosperms, Phytochemistry, Essential oils, Antimicrobial activity, Antioxidant activity, Ziziphora clinopodioides, Lamiaceae |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
