| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000452241 |
| ISSN: | 1984-8250 |
| Authors: | Chielle, Eduardo Ottobelli1 Vecchia, Daniele Dalla1 Rossi, Eliandra Mirei1 Chielle, Ana Paula Ottobelli1 Bonadiman, Beatriz da Silva Rosa2 Marafon, Filomena2 Bagatini, Margarete Dulce2 |
| Institutions: | 1Universidade do Oeste de Santa Catarina, Departamento de Ciencias da Vida, Sao Miguel do Oeste, Santa Catarina. Brasil 2Universidade Federal da Fronteira Sul, Departamento de Bioquimica e Biologia Molecular, Erechim, Rio Grande do Sul. Brasil |
| Year: | 2022 |
| Volumen: | 58 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | Phytochemicals present in detox juices and probiotics have demonstrated protective effects on cardiovascular risk factors. The consumption of these products alone modulate metabolic mechanisms and biomarkers. However, the effects of the combination of detox juice and probiotics have not yet been evaluated on atherogenic parameters. A randomized controlled study was carried out with 40 healthy volunteers (20 men and 20 women), aged between 18 and 50 years old. The volunteers ingested 200mL of juice for 30 days. Before and after supplementation, the anthropometric and lipid profiles and plasma concentrations of TBARS, Myeloperoxidase, Glutathione, Protein and non-protein Thiols and Vitamin C were analyzed. A reduction in LDL-c (p=0.05), triglycerides (p=0.05) and a significant increase in HDL-c (p=0.002) was observed. There was a significant decrease in the concentrations of TBARS (p=0.01), myeloperoxidases (p=0.02) and a significant increase in the Vitamin C and GSH (p=0.01). There wasn`t improvement in anthropometric parameters and total cholesterol. The findings highlight that supplementation with probiotic detox juice improves the lipid and antioxidant profile, suggesting a possible positive effect in reducing the risk of cardiovascular disease in healthy volunteers. Nevertheless, more robust researches with a prolonged treatment period should be conducted |
| Disciplines: | Química |
| Keyword: | Química de alimentos, Jugos desintoxicantes, Probióticos, Estrés oxidativo, Enfermedades cardiovasculares |
| Keyword: | Food chemistry, Probiotics, Detox juice, Oxidative stress, Cardiovascular diseases |
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