| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451487 |
| ISSN: | 1984-8250 |
| Authors: | Macedo, Isaac Yves Lopes de1 Alecrim, Morgana Fernandes1 Oliveira, Jerônimo Raimundo1 Torres, Ieda Maria Sapateiro1 Thomaz, Douglas Vieira1 Gil, Eric de Souza1 |
| Institutions: | 1Universidade Federal de Goias, Faculdade de Farmacia, Goiania, Goias. Brasil |
| Year: | 2020 |
| Volumen: | 56 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Piroxicam (PRX) was determined in pharmaceutical capsules with differential pulse voltammetry (DPV) in a three electrode system consisting of a pencil graphite electrode (PGE) as working electrode, a Pt wire and a reference electrode of Ag/AgCl/KCl 3 M. An irreversible oxidation peak was observed in Epa c.a. 0.6 V, which correlates to the oxidation of PRX. The coefficient of linear correlation obtained was 0.9946, with limit of detection of 2.1 µM and limit of quantification of 4.7 µM. PGE assays showed good analytical performance compared to high performance liquid chromatography and spectrophotometry, showing the potential to be further developed and employed in quick and simple analyses |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Química analítica, Cápsulas, Piroxicam, Electroanálisis, Voltametría de pulso diferencial |
| Keyword: | Medicinal chemistry, Analytical chemistry, Capsules, Electroanalysis, Piroxicam, Differential pulse voltammetry |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
