| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451344 |
| ISSN: | 1984-8250 |
| Authors: | Oliveira, Camila Freitas de1 Oliveira, Vinicius Bednarczuk1 Bobek, Vanessa Barbosa1 Rech, Katlin Suellen1 Betim, Fernando Cesar Martins1 Dias, Josiane de Fatima Gaspari1 Zanin, Sandra Maria Warumby1 Miguel, Obdulio Gomes1 Miguel, Marilis Dallarmi1 |
| Institutions: | 1Universidade Federal do Parana, Departamento de Farmacia, Curitiba, Parana. Brasil |
| Year: | 2020 |
| Volumen: | 56 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Psychotria fractistipula L.B.Sm, R.M. Klein & Delprete (Rubiaceae) is found in the existing Atlantic Forest in the South of Brazil, in the Paraná and Santa Catarina States. The members of Rubiaceae are characterized chemically by the presence of alkaloids, some pharmacological properties of which include antifungal, antibacterial, analgesic, antioxidant, antimutagenic, and antiviral activities. In this study, we report the results of anatomical, morphological, and histochemical analyses of the leaves and stems of the Rubiaceae family member, P. fractistipula. The anatomical analysis involved of light microscopy and scanning electron microscopy. Morpho-anatomical and histochemical characterization were made using standard methodology. The isolated compounds were identified by Nuclear Magnetic Resonance spectroscopic analysis. The following structures are highlighted as the distinctive features of the species: presence of petiolate leaves and a petiole base, leaf blade with smooth cuticle on both surfaces, paracytic stomata, and, dorsiventral mesophyll and presence of trichomes on the leaves and stems. Phytosteroids, identified as β-sitosterol and campesterol, were observed in the hexane fraction of the stem. Future studies should focus on the isolation of other fractions of interest and their characterization through specific biological and cytotoxicity assays |
| Disciplines: | Biología, Química |
| Keyword: | Angiospermas, Fitoquímica, Anatomía vegetal, Psychotria fractistipula, Rubiaceae |
| Keyword: | Angiosperms, Phytochemistry, Plant anatomy, Psychotria fractistipula, Rubiaceae |
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