| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451731 |
| ISSN: | 1984-8250 |
| Authors: | Arias Vázquez, Pedro Iván1 Arcila Novelo, Russell2 Ramírez Wakamatzu, María Antonieta3 |
| Institutions: | 1Universidad Juárez Autónoma de Tabasco, Comalcalco, Tabasco. México 2Universidad Autónoma de Yucatán, Mérida, Yucatán. México 3Centro Médico Aruku, Ciudad de México. México |
| Year: | 2022 |
| Volumen: | 58 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highlighting the mechanisms of action, forms of application and current clinical evidence. A systematic review was conducted in electronic databases, searching the terminology Ozone “or” Ozone therapy “and” SARS-CoV-2 or COVID-19 or Coronavirus. Results: nineteen studies were included; ten were editorials, comments, brief reports or reviews, and nine clinical studies. We found that ozone therapy could be favorable for treating patients infected with SARS-CoV-2 / COVID-19, through a direct antiviral effect, regulation of oxidative stress, immunomodulation and improvement of oxygen metabolism. Patients who were treated with ozone therapy responded favorably; therefore, ozone therapy appears to be a promising treatment for patients infected with SARS-CoV-2 / COVID-19. Its mechanism of action justifies its use as an adjuvant therapy; however, scientific evidence is based on case series and clinical trials are necessary to corroborate its effectiveness and safety |
| Disciplines: | Medicina |
| Keyword: | Terapéutica y rehabilitación, Neumología, COVID-19, Terapia adyuvante, Ozonoterapia |
| Keyword: | Therapeutics and rehabilitation, Pneumology, COVID-19, Ozone therapy, Adjuvant therapy |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
