| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451875 |
| ISSN: | 1984-8250 |
| Authors: | Rabby, Md Insiat Islam1 Hossain, Farzad2 Islam, Munadi Al3 Islam, A.K.M. Sadrul4 Akhi, Israt Jahan5 Akter, Ferdousi6 |
| Institutions: | 1Military Institute of Science and Technology, Department of Mechanical Engineering, Dhaka. Bangladesh 2Islamic University of Technology, Department of Mechanical and Production Engineering, Gazipur. Bangladesh 3Dhaka Medical College Hospital, Department of Medicine, Dhaka. Bangladesh 4The Ibn Sina Pharmaceutical Industry Ltd., Dhaka. Bangladesh 5Bangladesh Health Professions Institute, Department of Physiotherapy, Savar, Dhaka. Bangladesh 6Universiti Putra Malaysia, Faculty of Human Ecology, Serdang, Selangor. Malasia |
| Year: | 2022 |
| Volumen: | 58 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | The main aim of the paper is to assess whether vitamin C, vitamin D, and natural honey can be administered in the course of the COVID-19 pandemic for promising in line methods with recent evidence. Both systematic literature and clinical trial identification were conducted by searching various databases. A total 58 articles and 29 clinical trials were selected wherein 11 for vitamin C, 16 for vitamin D, and 2 for natural honey were identified for analysis. The high doses of vitamin C (i.e. ‘200 mg/kg body weight/day, divided into 4 doses’) has been found to reduce COVID-19 lung damage, various flu infections. Additionally, the high doses of vitamin C can shorten around 7.8% stay in the intensive care unit. At the same time, vitamin D can effectively protect from lung injury and acute respiratory infections whereas vitamin D deficiency severely affects 75% of the institutionalized people (serum 25(OH) D < 25 nmol/L). Meanwhile, natural honey which contains proteins (0.1-0.4%); ash (0.2%); water (15-17%) has potential antiviral effects and the ability to improve immunity. Therefore, the administration of vitamins and honey is the promising evidence-based approach for reducing fatalities, saving lives, and bringing the COVID-19 pandemic to a rapid end. It is believed that the utilization of vitamin C, vitamin D, and natural honey with the current treatment may be effective in treating COVID-19-caused fatal complications such as pneumonia. Therefore, high-level clinical studies are required on COVID-19 to administrate the effects of vitamins and natural honey |
| Disciplines: | Medicina |
| Keyword: | Virus, Farmacología, COVID-19, Prevención, Daño pulmonar, Vitamina C, Vitamina D, Miel, Actividad antiviral |
| Keyword: | Virus, Pharmacology, COVID-19, Prevention, Lung damage, Vitamin C, Vitamin D, Honey, Antiviral activity |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
