Journal: | Brazilian Journal of Pharmaceutical Sciences |
Database: | PERIÓDICA |
System number: | 000450956 |
ISSN: | 1984-8250 |
Authors: | Fabri, Natasha Tiemi1 Gatto, Larissa Junqueira1 Furusho, Alethéia Santos1 Garcia, Meira Janette Ballestros2 Marques, Francisco de Assis2 Miguel, Marilis Dallarmi1 Montrucchio, Deise Prehs1 Zanin, Sandra Maria Warumby1 Miguel, Obdulio Gomes1 Dias, Josiane de Fátima Gaspari1 |
Institutions: | 1Universidade Federal do Parana, Departamento de Farmacia, Curitiba, Parana. Brasil 2Universidade Federal do Parana, Departamento de Quimica, Curitiba, Parana. Brasil |
Year: | 2019 |
Volumen: | 55 |
Country: | Brasil |
Language: | Inglés |
Document type: | Artículo |
Approach: | Experimental, aplicado |
English abstract | The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells |
Disciplines: | Biología, Química |
Keyword: | Fitoquímica, Angiospermas, Aceites esenciales, Composición química, Actividad biológica, Capacidad antioxidante, Espatulenol, Ocotea diospyrifolia, Lauraceae |
Keyword: | Phytochemistry, Angiosperms, Essential oils, Chemical composition, Biological activity, Antioxidant capacity, Spathulenol, Ocotea diospyrifolia, Lauraceae |
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