| Journal: | Brazilian Journal of Pharmaceutical Sciences |
| Database: | PERIÓDICA |
| System number: | 000451259 |
| ISSN: | 1984-8250 |
| Authors: | Mosbah, Habib1 Sassi, Ahlem Ben2 Chahdoura, Hassiba1 Snoussi, Mejdi3 Flamini, Guido4 Achour, Lotfi1 Selmi, Boulbaba1 |
| Institutions: | 1Higher Institute of Biotechnology of Monastir, Laboratory of Bioresources: Integrative Biology and Valorization, Monastir. Túnez 2University of Monastir, Faculty of Pharmacy, Monastir. Túnez 3Higher Institute of Biotechnology of Monastir, Laboratory of Genetic, Biodiversity and Valorization of Bioesources, Monastir. Túnez 4Universita di Pisa, Dipartimento di Farmacia, Pisa, Toscana. Italia |
| Year: | 2020 |
| Volumen: | 56 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The in-vitro antioxidant activity of Rhaponticum acaule essential oil (RaEO) was evaluated using β-carotene/linoleic acid bleaching, chelating activity, and lipid peroxidation inhibition (TBARS) assays. The antimicrobial activity of RaEO was assessed by disc diffusion and microdilution methods against 8 bacteria and 4 yeast. Finally, the allelopathic activity of RaEO on the seed germination and the shoot and root elongation of lettuce (Lactuca sativa L.) seedlings were investigated. According to our results, the RaEO exhibited significant antioxidant activity, similar to those of standards (BHT and ascorbic acid) with IC50 values of 0.042 and 0.045 mg/mL obtained by β-carotene bleaching and TBARS assays, respectively. On the other hand, despite its interesting ferrous chelating activity, RaEO possesses moderate IC50 value (0.35 mg/mL) as compared with that of EDTA (0.015 mg/mL). RaEO exhibited a strong antimicrobial activity against all the tested microorganisms, with IZ, MIC and MBC values being in the range of 7.67 ± 0.58 to 13.33 ± 0.58 mm, 1.25 to 5.00 and 5.00 to 10.00 mg/mL, respectively. The results reveled also that RaEO inhibited the shoot and root growth of Lactuca sativa L. seedlings. Our data suggested that the RaEO had pharmaceutical benefits and could be used as a potential natural herbicide resource |
| Disciplines: | Química |
| Keyword: | Fitoquímica, Aceites esenciales, Actividad antioxidante, Actividad antimicrobiana, Alelopatía, Rhaponticum acaule, Asteraceae |
| Keyword: | Phytochemistry, Essential oils, Antioxidant activity, Antimicrobial activity, Allelopathy, Rhaponticum acaule, Asteraceae |
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