Revista: | Brazilian Journal of Pharmaceutical Sciences |
Base de datos: | PERIÓDICA |
Número de sistema: | 000451838 |
ISSN: | 1984-8250 |
Autores: | Hien, Chu Thi Thu1 Hoa, Phu Thi2 Thuy, Nguyen Hai3 Dung, Tran Huu4 |
Instituciones: | 1Buon Ma Thuot University, Faculty of Pharmacy, Buon Ma Thuot, Dak Lak. Vietnam 2Hue University University of Medicine & Pharmacy, Department of Biochemistry, Ngo Quyen, Hue City. Vietnam 3Hue University University of Medicine & Pharmacy, Department of Internal Medicine, Ngo Quyen, Hue City. Vietnam 4Hue University University of Medicine & Pharmacy, Faculty of Pharmacy, Ngo Quyen, Hue City. Vietnam |
Año: | 2022 |
Volumen: | 58 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, aplicado |
Resumen en inglés | Resistant starch is particularly concerned with beneficial effects in regulating blood glucose concentration and lipid metabolism, reducing the risk of diabetes and cardiovascular diseases. This study aimed to validate the effects of wheat starch acetate containing 32.1% resistant starch on postprandial blood glucose response and lipid profile on obesity, dyslipidemia Swiss mice induced by a high-fat diet. The result showed that there was a restriction on postprandial hyperglycemia and remained stable for 2 hours after meal efficiently comparing with the control group fed natural wheat starch. Simultaneously, when maintaining the dose of 5g/kg once or twice a day for 8 weeks, wheat starch acetate to be able to reduce body weight and blood glucose, triglyceride, cholesterol levels compared to the control group (p<0.05) |
Disciplinas: | Química, Medicina |
Palabras clave: | Metabolismo y nutrición, Farmacología, Medicina experimental, Acetato de almidón, Dislipidemia, Obesidad, Colesterol, Glucosa |
Keyword: | Metabolism and nutrition, Pharmacology, Experimental medicine, Acetate starch, Dyslipidemia, Obesity, Glucose, Cholesterol |
Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |