| Journal: | Brazilian archives of biology and technology |
| Database: | PERIÓDICA |
| System number: | 000374042 |
| ISSN: | 1516-8913 |
| Authors: | Farias, Luana d'Avila1 Pereira, Camila Bugnotto2 Machado, Gustavo3 Schmidt, Cleber Alberto4 Vargas, Agueda Castagna de1 |
| Institutions: | 1Universidade Federal de Santa Maria, Departamento de Medicina Veterinaria Preventiva, Santa Maria, Rio Grande do Sul. Brasil 2Universidade Federal de Santa Maria, Programa de Pos-Graduacao em Ciencias Farmaceuticas, Santa Maria, Rio Grande do Sul. Brasil 3Universidade Federal do Rio Grande do Sul, Departamento de Medicina Veterinaria Preventiva, Porto Alegre, Rio Grande do Sul. Brasil 4Universidade Federal da Bahia, Departamento de Medicamento, Salvador, Bahia. Brasil |
| Year: | 2013 |
| Season: | Nov-Dic |
| Volumen: | 56 |
| Number: | 6 |
| Pages: | 942-947 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | This study aimed to evaluate and select different dermatological bases incorporated with propolis for veterinary use as well as to analyze the chemical compounds of the propolis hydroalcoholic extract by LC-MS/MS. Thus, formulations were submitted to accelerated stability tests under different temperatures and to mechanical stress, and evaluated for the appearance, color, odor, pH, viscosity, spreadability, and the mean size of the dispersed globules from the internal phase during a period of three months. The creamy gel formulation showed satisfactory results for all the evaluated items with an excellent capability to incorporate the hydroalcoholic extract of propolis associated to the maintenance of its physicochemical properties. The propolis used in this study had been shown to possess antibacterial and antifungal in vitro activity against the main microorganisms responsible for such diseases. Therefore, the propolis creamy gel described here could be a promising formulation for use in the veterinary medicine |
| Disciplines: | Medicina veterinaria y zootecnia, Química |
| Keyword: | Medicina veterinaria, Química farmacéutica, Propóleo, Fitoterapia, Actividad antimicrobiana, Acido cafeico, Estabilidad química |
| Keyword: | Veterinary medicine and animal husbandry, Chemistry, Veterinary medicine, Medicinal chemistry, Propolis, Phytotherapy, Antimicrobial activity, Caffeic acid, Chemical stability |
| Full text: | Texto completo (Ver HTML) |
