Achievements and challenges in controlling Chagas disease



Título del documento: Achievements and challenges in controlling Chagas disease
Revista: Boletín médico del Hospital Infantil de México
Base de datos: PERIÓDICA
Número de sistema: 000347111
ISSN: 1665-1146
Autores: 1
2
3
Instituciones: 1Universidad de Los Andes, Instituto Experimental José Witremundo Torrealba, Trujillo, La Libertad. Venezuela
2Emory University, School of Medicine, Atlanta, Georgia. Estados Unidos de América
3Hospital Infantil de México "Federico Gómez", México, Distrito Federal. México
Año:
Periodo: Mar-Abr
Volumen: 68
Número: 2
Paginación: 111-119
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés American trypanosomiasis or Chagas disease continues to endanger the lives of many million people in Latin America, and through travel and population migration there is a risk of congenital cases in nonendemic settings. Substantial improvements in the transmission of the disease have been achieved through vector control and blood–bank screening. However, vector–borne transmission remains the main mode of acquisition of infection in many settings coupled with congenital transmission and food–borne and accidental exposure through transplantation or laboratory exposure. The main sites of affection include the heart and gastrointestinal tract. Antiparasitic treatment of indeterminate forms is successful in many cases by delaying the risk of progression of cardiomyopathy, but treatment of chronic chagasic cardiomyopathy remains mainly supportive. The BENEFIT trial that will be completed by late 2011 or early 2012 will provide evidence for or against treating chronic symptomatic forms. Control or eliminating Chagas disease transmission coupled with decreasing the associated burden of disease in Latin America will promote better health and social and economic development among the most impoverished populations in the region
Disciplinas: Medicina
Palabras clave: Microbiología,
Salud pública,
Enfermedades tropicales,
Enfermedad de Chagas,
Epidemiología,
Cardiomiopatías,
Control de enfermedades
Keyword: Medicine,
Microbiology,
Public health,
Tropical diseases,
Chagas disease,
Epidemiology,
Cardiomyopathies,
Disease control
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