Chemical composition, cytotoxicity and larvicidal activity against Aedes aegypti of essential oils from Vitex gardineriana Schauer
Document title: Chemical composition, cytotoxicity and larvicidal activity against Aedes aegypti of essential oils from Vitex gardineriana Schauer
Journal: Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas
Database: PERIÓDICA
System number: 000417479
ISSN: 0717-7917
Authors: 1
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Institutions: 1Universidade Estadual do Ceara, Fortaleza, Ceara. Brasil
2Universidade Estadual Vale do Acarau, Centro de Ciencias Exatas e Tecnologia, Sobral, Ceara. Brasil
Year:
Season: May
Volumen: 17
Number: 3
Pages: 302-309
Country: Chile
Language: Inglés
Document type: Artículo
Approach: Experimental, analítico
Spanish abstract Vitex gardneriana Schauer (Lamiaceae) popularmente conocido como "jaramataia", es un arbusto que se encuentra comúnmente en el bioma de caatinga ubicado en el noreste de Brasil. En medicina popular, sus hojas se han utilizado como analgésicos y agentes antiinflamatorios. La composición química de los aceites esenciales de las hojas obtenidas por hidrodestilación fue analizada e identificada por GC-MS y GC-FID y mostrando un total de 26 constituyentes (95.9%) siendo 2 monoterpenos (0.4%) y 24 sesquiterpenos (95.4%). Los componentes principales fueron cis-calamenene (29.7%), 6,9-guaiadiene (14.5%) y caryophyllene oxide (14.0%). El aceite esencial ha demostrado una alta actividad larvicida contra Aedes aegypti (CL50 = 28.0 μg/mL). En la evaluación del bioensayo con Artemia salina, el aceite esencial demostró CL50 = 98.11 μg/mL. Además, el aceite esencial no mostró citotoxicidad (IC50 > 2.5 mg / mL) mediante el ensayo de hemólisis
English abstract Vitex gardneriana Schauer (Lamiaceae) popularly known as “jaramataia”, is a shrub commonly found in caatinga biome located in Northeast Brazil. In folk medicine, its leaves have been used as analgesic and anti-inflammatory agents. The chemical composition of the essential oil from leaves obtained by hydrodistillation was analyzed and identified by GC-MS and GC-FID and showing a total of 26 constituents (95.9%) being 2 monoterpenes (0.4%) and 24 sesquiterpenes (95.4%). The main constituents identified were cis-calamenene (29.7%), 6,9-guaiadiene (14.5%) and caryophyllene oxide (14.0%). The essential oil has been demonstrated high larvicidal activity against Aedes aegypti (LC50 = 28.0 μg/mL). In the evaluation of the bioassay with Artemia salina the essential oil showed LC50 = 98.11 μg/mL. In addition, the essential oil did not show cytotoxicity (IC50 > 2.50 mg/mL) by the hemolysis assay
Disciplines: Biología,
Química
Keyword: Angiospermas,
Fitoquímica,
Vitex gardineriana,
Aceites esenciales,
Control biológico,
Artemia salina,
Actividad larvicida,
Citotoxicidad
Keyword: Angiosperms,
Phytochemistry,
Vitex gardineriana,
Essential oils,
Biological control,
Artemia salina,
Larvicidal activity,
Cytotoxicity
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