Treatment of trigeminal neuralgia with low doses of topiramate
Document title: Treatment of trigeminal neuralgia with low doses of topiramate
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000330747
ISSN: 0004-282X
Authors: 1
1
1
Institutions: 1Santa Casa de Misericordia de Vitoria, Escola Superior de Ciencias, Vitoria, Espirito Santo. Brasil
Year:
Season: Sep
Volumen: 65
Number: 3b
Pages: 792-794
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Descriptivo
English abstract Topiramate was administered to eight patients with classical trigeminal neuralgia with or without previous symptomatic therapy with other antiepileptic drugs. The topiramate doses ranged from 50 to 100 mg a day, according to the clinical response and the reported side effects. Three patients had complete symptoms remission, three reported moderate improvement, and the treatment was not effective in two. The most frequently registered side effects were dizziness, somnolence and weight loss. Topiramate can be considered an alternative treatment for patients with trigeminal neuralgia
Portuguese abstract Oito pacientes com neuralgia do trigêmeo, com ou sem tratamentos prévios com anticonvulsivantes, foram submetidos a tratamento com topiramato. As doses de topiramato variaram de 50 a 100 mg ao dia, de acordo com a resposta clínica e com os efeitos colaterais relatados. Três pacientes obtiveram remissão completa, três relataram melhora parcial e o tratamento com topiramato foi ineficaz em dois pacientes. Os efeitos colaterais mais frequentemente citados foram tontura, sonolência e perda de peso. O topiramato pode ser considerado uma alternativa potencialmente eficaz para o tratamento de pacientes com neuralgia do trigêmeo
Disciplines: Medicina
Keyword: Farmacología,
Neurología,
Neuralgia,
Trigémino,
Topiramato,
Antiepilépticos
Keyword: Medicine,
Neurology,
Pharmacology,
Neuralgia,
Trigeminus,
Topiramate,
Antiepileptic agents
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